RESEARCH ARTICLE
Bone Scan with Confusing Appearance: Superscan or Metabolic Disorder
Stefan Gratz*, 1, 2, Wolf Kaiser2, Thomas M. Behr1
Article Information
Identifiers and Pagination:
Year: 2008Volume: 2
First Page: 109
Last Page: 110
Publisher Id: TOMIJ-2-109
DOI: 10.2174/1874347100802010109
Article History:
Received Date: 02/10/2008Revision Received Date: 20/11/2008
Acceptance Date: 23/11/2008
Electronic publication date: 23/12/2008
Collection year: 2008
© 2018 Gratz et al.
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
We present a patient with metastatic prostate cancer with known bone involvement and unknown osteomyelofibrosis. It has the general appearance of a superscan, with homogeneously increased tracer uptake and no visualization of the kidneys. However, while a superscan should have greater uptake in the axial skeleton compared to the appendicular skeleton, this scan is reverse, raising the suspicion of an overlying metabolic bone disorder. Subsequent laboratory-, bioptical findings confirmed a myeloproliferative syndrome with osteomyelofibrosis. As such, this scan demonstrates that in a patient with both affiliations, metabolic bone disease can override even severe osseous metastases on a bone scan.
Keywords: Prostate cancer, metastasis, metabolic disorder, bone scan.
