RESEARCH ARTICLE
A Polynomial Fitting Improved Bayesian Reconstruction Method for Whole Brain Volumetric MRSI Metabolite Images
Yufang Bao1, *, Andrew Maudsley2
Article Information
Identifiers and Pagination:
Year: 2013Volume: 7
First Page: 1
Last Page: 8
Publisher Id: TOMIJ-7-1
DOI: 10.2174/1874347101307010001
Article History:
Received Date: 04/07/2012Revision Received Date: 09/09/2012
Acceptance Date: 12/09/2012
Electronic publication date: 7/2/2013
Collection year: 2013
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
In this paper, a polynomial fitting improved Bayesian approach is proposed for the reconstruction of volumetric metabolite images from long echo time (TE) whole brain proton magnetic resonance spectroscopic imaging (MRSI) data. The proposed algorithm uses a modified EM (expectation maximization) algorithm that takes into account the partial volume effects contained inside a thick slice MRSI. It incorporates high resolution volumetric magnetic resonance imaging (MRI) as a priori information. It further integrates the polynomial fitting method to smooth out artificial edges before the high resolution metabolite images are reconstructed. Our proposed reconstruction method has successfully extended our existing reconstruction of two dimensional (2D) metabolite images to 3D cases. The experimental results show that resolution enhanced volumetric metabolite images are reconstructed.
